The number of molecules of a nucleotide of molecular weight 300 g/mol present in 10 picomoles is ______ x 10^12 (round off to 2 decimal places).
GATE 2020 BT Q.21: solution and answer
Answer and solution
ANSWER
10 picomoles of the nucleotide contain molecules, so the blank is 6.02.
Official answer: 5.99 to 6.05Source: Official answer key, GATE 2020 BT (IIT Delhi)
The number of molecules depends only on the amount in moles. The molecular weight of 300 g/mol would be needed only to convert the amount to a mass, so here it is not used.
Convert the amount: .
One mole contains Avogadro's number of molecules: .
Multiply: molecules.
Rounded to 2 decimal places, the blank is , since the number is written as .
KEY IDEA
Number of molecules = moles × Avogadro's number. The molecular weight is irrelevant when the amount is already given in moles. 1 pmol = mol.
WATCH OUT FOR
Using the 300 g/mol molecular weight (for example dividing 10 by 300 or multiplying by it) even though the amount is already in moles. Another slip is mis-converting pico () as or .
From the GATE 2020 BT paper. Every question of this paper · Download the full paper · All 12 Biomolecules questions, with notes
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