FLAGSHIPGATE · BT
GATE — Biotechnology
A flagship program for GATE BT preparation — learn from the pioneers.
4.9692 learner reviews
⏱ Full Syllabus📊 Basic to advance levels🎯 Classroom & Online Courses
- Interactive teaching-learning + recorded class support
- PYQ & other problem solving + regular tests
- 1:1 mentorship + doubt clearing system
Recent GATE toppers
AIR 8 · IISc BangaloreAIR 9 · IIT KharagpurAIR 18 · IIT Guwahati
Mode
Target year
Course fee
₹19,999₹39,99950% OFF
✓
Recording access till exam✓
1:1 mentorship support✓
Doubt discussion forum✓
Post examination guidance800+
Class Hours
5K+
Practice Questions
120+
Assessment Tests
1:1
Mentorship Sessions
Curriculum
What we will cover
01Engineering Mathematics+
- Linear Algebra: Matrices and determinants; Systems of linear equations; Eigen values and Eigen vectors.
- Calculus: Multivariable calculus (limits, continuity, and differentiability); Partial derivatives, maxima and minima; Sequences and series; Test for convergence. Multivariable calculus: Gradient, divergence, and curl (for applications in fluid mechanics, transport processes, etc.).
- Differential Equations: Linear and nonlinear first order ODEs, higher order ODEs with constant coefficients; Cauchy's and Euler's equations; Laplace transforms.
- Probability and Statistics: Mean, median, mode and standard deviation; Random variables; Poisson, normal and binomial distributions; Correlation and regression analysis; Bayesian Statistics.
- Numerical Methods: Solution of linear and nonlinear algebraic equations; Integration by trapezoidal and Simpson's rule; Single step method for differential equations.
02General Biology+
- Biochemistry: Biomolecules - structure and function; Biological membranes - structure, membrane channels and pumps, molecular motors, action potential and transport processes; Basic concepts and regulation of metabolism of carbohydrates, lipids, amino acids and nucleic acids; Metabolism: Regulation of metabolism of carbohydrates, lipids, amino acids, and nucleic acids; Detailed pathways like glycolysis, citric acid cycle, and fatty acid oxidation; Photosynthesis, respiration and electron transport chain; Enzymes - Classification, catalytic and regulatory strategies; Enzyme kinetics - Michaelis-Menten equation; Enzyme inhibition - competitive, non-competitive and uncompetitive inhibition.
- Microbiology: History of Microbiology, Bacterial classification and diversity; Bacterial cell wall composition, Gram positive and Gram-negative bacteria, Archea, Methods in microbiology; Microbial growth and nutrition; Operon- Lac, Trp and Ara operon, Nitrogen fixation; Microbial diseases and host-pathogen interactions; Antibiotics and antimicrobial resistance, Two-component system ( TCS), bacterial communication, Viruses - structure and classification.
- Immunology: Primary and Secondary lymphoid organs; Innate immunity and Inflammation; Cytokines and Chemokines; Complement system; Effector responses: Cellular and Humoral Immunity; Molecular basis of Antibody diversity and function; Polyclonal and Monoclonal antibodies; T-cell and B-cell development; Memory responses; Major Histocompatibility complex (MHC); Antigen processing and presentation; Regulation of immune responses; Immune tolerance; Hypersensitivity; Autoimmunity and Immunodeficiency; Graft vs Host disease; Immunization and vaccines.
03Genetics, Cellular and Molecular Biology+
- Genetics and Evolutionary Biology: Mendelian inheritance; Gene interaction; Complementation; Linkage, recombination and chromosome mapping; Extra chromosomal inheritance; Microbial genetics - transformation, transduction and conjugation; Bacterial gene mapping; Horizontal gene transfer and transposable elements; Chromosomal variation; Sex Determination; Genetic disorders; Population genetics; Epigenetics; Selection and inheritance; Adaptive and neutral evolution; Genetic drift; Species and speciation.
- Cell Biology: Eukaryotic cell structure; Cell cycle and cell growth control; Cell-cell communication; Cell signalling and signal transduction; Non-cell autonomous cell signalling; Post-translational modifications; Protein trafficking; Cell death and autophagy; Extra-cellular matrix.
- Molecular Biology: Molecular structure of genes and chromosomes; Mutations and mutagenesis; Regulation of gene expression; Nucleic acid - replication, transcription, splicing, translation and their regulatory mechanisms; Non-coding and micro RNA; RNA interference; DNA damage and repair
04Fundamentals of Biological Engineering+
- Bioreaction Engineering: Rate law, zero and first order kinetics; (More advanced kinetic models, including Michaelis-Menten kinetics for enzyme reactions. Inhibition kinetics: Competitive, non-competitive, and uncompetitive inhibition in enzyme catalysis); Ideal reactors - batch, mixed flow and plug flow; Enzyme immobilization, diffusion effects - Thiele modulus, effectiveness factor, Damkoehler number; Kinetics of cell growth, substrate utilization and product formation; Structured and unstructured models; Batch, fed-batch and continuous processes; Microbial and enzyme reactors; Optimization and scale up (Design and operation of microbial reactors (e.g., fermentation reactors) and enzyme reactors (e.g., immobilized enzyme systems); Case studies on the use of microbial reactors in large-scale production (e.g., antibiotics, biofuels).
- Upstream and Downstream Processing: Media formulation and optimization; Sterilization of air and media; Filtration - membrane filtration, ultra filtration; Centrifugation - high speed and ultra; Cell disruption; Principles of chromatography - ion exchange, gel filtration, hydrophobic interaction, affinity, GC, HPLC and FPLC; Extraction, adsorption and drying; Measurement devices; Valves; First order and second order systems; Feedback and feed forward control; Types of controllers – proportional, derivative and integral control; Tuning of controllers.
05Plant, Animal and Microbial Biotechnology+
- Plants: Totipotency; Cell fate transition, direct and indirect organogenesis, regeneration of plants; Plant growth regulators and elicitors; Tissue culture and cell suspension culture system - methodology, kinetics of growth and nutrient optimization; Production of secondary metabolites; Hairy root culture; Plant products of industrial importance; Artificial seeds; Somaclonal variation; Protoplast, protoplast fusion - somatic hybrid and cybrid; Transgenic plants - direct and indirect methods of gene transfer techniques; Selection marker and reporter gene; Plastid transformation.
- Animals: Culture media composition and growth conditions; Animal cell and tissue preservation; Anchorage and non-anchorage dependent cell culture; Kinetics of cell growth; Micro & macro- carrier culture; Hybridoma technology; Stem cell technology; Animal cloning; Transgenic animals; Knock-out and knock-in animals.
- Microbes: Production of biomass and primary/secondary metabolites - Biofuels, bioplastics, industrial enzymes, antibiotics; Large scale production and purification of recombinant proteins and metabolites; Clinical-, food- and industrial- microbiology; Screening strategies for new products.
06Recombinant DNA technology and Other Tools in Biotechnology+
- Recombinant DNA technology: Restriction and modification enzymes; Vectors - plasmids, bacteriophage and other viral vectors, cosmids, Ti plasmid, bacterial and yeast artificial chromosomes; Expression vectors; cDNA and genomic DNA library Gene isolation and cloning, strategies for production of recombinant proteins; Transposons and gene targeting, Recombination-based gene cloning.
- Molecular tools: Polymerase chain reaction; DNA/RNA labelling and Sangers and next generation sequencing; Southern and northern blotting; In-situ hybridization; DNA fingerprinting, RAPD, RFLP; Site-directed mutagenesis; CRISPR-Cas; Biosensing and biosensors; DNA-protein and protein-protein interaction tools; Genomics and proteomics-based approaches.
- Analytical tools: Principles of microscopy - light, electron, fluorescence and confocal; Principles of spectroscopy- UV, visible, fluorescence, CD, IR, FT-IR, MS, NMR; Electrophoresis; Micro- arrays; Enzymatic assays; Immunoassays - ELISA, RIA, immunohistochemistry; Immunoblotting; Flow cytometry; Whole genome and ChIP sequencing.
- Computational tools: Bioinformatics resources and search tools; Sequence and structure databases; Sequence analysis - sequence file formats, scoring matrices, alignment, phylogeny; Genomics, proteomics, metabolomics; Gene prediction; Functional annotation; Secondary structure and 3D structure prediction; Knowledge discovery in biochemical databases; Metagenomics; Metabolic engineering and systems biology.
07General Aptitude+
- Verbal Aptitude: Basic English grammar (tenses, articles, adjectives, prepositions, conjunctions, verb-noun agreement, and other parts of speech); basic vocabulary — words, idioms, and phrases in context; reading and comprehension; narrative sequencing.
- Quantitative Aptitude: Data interpretation (data graphs, 2- and 3-dimensional plots, maps, and tables); numerical computation and estimation (ratios, percentages, powers, exponents and logarithms, permutations and combinations, and series); mensuration and geometry; elementary statistics and probability.
- Analytical Aptitude: Logic — deduction and induction; analogy; numerical relations and reasoning.
- Spatial Aptitude: Transformation of shapes (translation, rotation, scaling, mirroring, assembling, and grouping); paper folding, cutting, and patterns in 2 and 3 dimensions.
Salient Features
What you'll get in this course
✓
800+ hours of interactive classes
✓
Subject-wise best faculty members
✓
Proper concept & analytical skill development
✓
Recorded video class support for revision
✓
3000+ problems & question discussion in class
✓
Additional 200+ hours of problem-solving videos
✓
Chapter-wise updated workbooks for practice
✓
Topic-wise PYQ discussion for each subject
✓
Systematic revision & doubt clearance
✓
Complete mock test series with 120+ tests
✓
Test series includes subject-wise, sectional & full-length tests
✓
Test-paper analysis report for assessment
Career Outcomes
What you'll be able to do
✓
A strong GATE BT rank opens the door to M.Tech, M.E., MS-by-research and direct-PhD admission in biotechnology and allied life-science programmes at the IITs, IISc, NITs, IIITs and other CFTIs.
✓
Qualifying for a sponsored M.Tech seat lets you pursue full-time postgraduate study supported by a government or institute assistantship with a monthly stipend.
✓
Because biotechnology has very limited PSU recruitment through GATE, a good score is best leveraged toward research and R&D pathways — for example project-associate and fellowship openings at CSIR institutes, DBT-supported centres and ICMR labs — rather than the core-engineering PSU route.
✓
Your GATE score stays valid for three years, so you can pursue project-associate positions, JRF-style research fellowships and PhD assistantships across several admission and recruitment cycles.
✓
This qualification points you toward a research and development career in molecular biology, genetic engineering and bioprocess-based industries spanning pharma, biologics, food and environmental biotechnology, and academia.
Ratings & Reviews
What learners say
4.9
692 reviews
5
92%
4
6%
3
1%
2
0%
1
0%
“IAE Academy had been instrumental in my GATE journey. The classes were interesting and the online exams were very helpful in my preparation. I would urge everyone to join IAE Academy if they wish to succeed in GATE.”
DG
Debrupendu Gupta
GATE 2025 · AIR 8 · IISc Bangalore
“Securing AIR 9 in GATE allowed me to pursue M.Tech at IIT Kharagpur. IAE Academy's guidance on perseverance and time management complemented my hard work, enabling me to crack the exam on my very first attempt.”
AD
Anindita Dhara
GATE 2021 · AIR 9 · IIT Kharagpur
“With IAE Academy's structured study plan, doubt-solving sessions and constant guidance, I was able to achieve AIR 18 in GATE and am now pursuing M.Tech in Biotechnology from IIT Guwahati.”
SN
SK Natasa
GATE 2025 · AIR 18 · IIT Guwahati
FAQ
Common questions
Can I join the GATE program in my 1st year of B.Tech?+
The engineering subjects in the GATE syllabus generally begin aligning with your B.Tech course from the 3rd semester onwards, so the core GATE classes are best attended after you complete your first year. During that first year, we run foundation classes that build the basics you'll need to grasp GATE subjects easily later on. To plan the right starting point for you, book a free counselling with our experts.
Should I join online or offline classes?+
Offline classes tend to be more engaging and make it easier to stay focused throughout your preparation — but a few other factors matter too. If you have strong self-motivation, focus, and critical-thinking ability, you can achieve very good results through the online program as well. However, if you need personalised guidance, end-to-end monitoring, and continuous motivation during your preparation, the classroom (offline) program is the better choice: the institute takes full responsibility for guiding you through a systematic process, and the classroom environment itself helps you stay focused.
Is there any EMI facility or discount available?+
We're always happy to support students who genuinely need it. For financial queries like these, please reach out to our helpline, and our team will guide you through the available options.
Ready to begin?
Enquire now or book a free counselling session with a mentor to see if this programme is right for you.